Alcaraz favored at US Open with Sinner injured

Carlos Alcaraz enters the US Open as the betting favorite at +250 odds (per DraftKings) to retain his title, boosted by the absence of injured world number one Jannik Sinner. Alcaraz, the reigning US Open champion, opens his title defense against Safiullin. Sinner's injury has significantly shifted the betting landscape heading into the tournament.